Expression :

Owner Public
URN urn:agi-Expression:inout-urn:agi-cas:50-02-2:out-urn:agi-llid:5465::positive
Entities dexamethasone --+> PPARA
References 4
Connectivity 2
Effect positive

Organism Mus musculus
CellLineName 3T3 L1
Journal Mol. Endocrin
Journal Reference v14 i2 p307 (2000)
Journal Link http://mend.endojournals.org/cgi/content/full/14/2/307
MedLine Reference 10674402:1063
Sentence MIX, DEX, and insulin efficiently induced PPAR mRNA in 3T3-L1 cells but much less efficiently in NIH-3T3 cells (Fig. 2 , D and C, lane 1).

Organism Mus musculus
Journal J. Biol. Chem
CellType lymphocyte
Journal Reference v277 i9 p6838 (2002)
Journal Link http://www.jbc.org/cgi/content/full/277/9/6838
MedLine Reference 11726654:1182
Sentence Dexamethasone induces PPAR alpha expression in lymphocytes.

Organism Rattus norvegicus
CellType hepatocyte
MedLine Reference 9354589:6
Sentence It was found that IL-1beta and IL-6 both repress the induction of PPAR alpha expression exerted by the combined action of clofibric acid and dexamethasone.

Organ liver
MedLine Reference 9610365:5
Sentence The expression of PPAR alpha in cultured HAEC, which were induced by dexamethasone, was inhibited by insulin.