| Owner | Public |
|---|---|
| URN | urn:agi-Expression:inout-urn:agi-cas:4602-84-0:out-urn:agi-llid:5465::positive |
| Entities | farnesol --+> PPARA |
| References | 3 |
| Connectivity | 2 |
| Effect | positive |
| Journal | Mol. Cancer Ther |
|---|---|
| CellType | keratinocyte |
| Journal Reference | v1 i5 p357 (2002) |
| Journal Link | http://mct.aacrjournals.org/cgi/content/full/1/5/357 |
| Organ | skin |
| MedLine Reference | 12489852:1062 |
| Sentence | Farnesol also stimulates PPAR -dependent differentiation in epidermal keratinocytes ( 45 ). |
| Organism | Mus musculus |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v275 i15 p11484 (2000) |
| Journal Link | http://www.jbc.org/cgi/content/full/275/15/11484 |
| Organ | skin |
| MedLine Reference | 10753967:1248 |
| Sentence | Furthermore, in cells that do not contain endogenous PPARs, we demonstrate that PPARalpha is activated by farnesol, similar to studies by another laboratory ( 45 ). |
| MedLine Reference | 11779144:5 |
|---|---|
| Sentence | In addition, the cerivastatin-induced transcriptional activation of PPARalpha/RXRalpha was decreased by addition of mevalonate, farnesol, geranylgeraniol, or cholesterol and by co-transfection with sterol regulatory element-binding protein-1 (SREBP-1). |