| Owner | Public |
|---|---|
| URN | urn:agi-Expression:inout-urn:agi-llid:5465:out-urn:agi-enz:2.7.1.99::positive |
| Entities | pyruvate dehydrogenase kinase <+-- PPARA |
| References | 2 |
| Connectivity | 2 |
| Effect | positive |
| Organism | Rattus norvegicus |
|---|---|
| CellLineName | 3T3 L1 |
| Journal | Endocrin. Metabol |
| CellType | adipocyte |
| Journal Reference | v285 i1 pE130 (2003) |
| Journal Link | http://ajpendo.physiology.org/cgi/content/full/285/1/E130 |
| MedLine Reference | 12637257:1259 |
| Sentence | Regulation of pyruvate dehydrogenase kinase expression by peroxisome proliferator-activated receptor-alpha ligands, glucocorticoids, and insulin. |
| Organism | Mus musculus |
|---|---|
| Journal | Heart Circul |
| Journal Reference | v285 i1 pH270 (2003) |
| Journal Link | http://ajpheart.physiology.org/cgi/content/full/285/1/H270 |
| Organ | heart |
| MedLine Reference | 12663261:1020 |
| Sentence | Because the transcriptional regulator peroxisome proliferator-activated receptor (PPAR)-alpha increases PDK expression in some tissues, we examined what role PPAR-alpha has in regulating glucose oxidation in hearts from mice overexpressing PPAR-alpha (MHC-PPAR-alpha mice). |